Ontology highlight
ABSTRACT:
SUBMITTER: Regnery S
PROVIDER: S-EPMC7600477 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Regnery Sebastian S Eichkorn Tanja T Weykamp Fabian F Held Thomas T Dinges Lisa-Antonia LA Schunn Fabian F Winter Hauke H Thomas Michael M Debus Jürgen J El Shafie Rami A RA Adeberg Sebastian S Hörner-Rieber Juliane J
Cancers 20201005 10
Stereotactic body radiotherapy (SBRT) to central and ultracentral lung tumors carries a risk of excessive toxicity. This study analyzed changes in pulmonary function tests (PFT) and their correlation with overall survival (OS) in 107 patients following central (<i>n</i> = 62) or ultracentral (<i>n</i> = 45) lung SBRT. Ultracentral location was defined as planning target volume overlap with the proximal bronchial tree (PBT). Vital capacity (VC) (-0.3 l, absolute -9.4% of predicted, both <i>p</i> ...[more]