Ontology highlight
ABSTRACT:
SUBMITTER: Bande M
PROVIDER: S-EPMC7600503 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Bande Manuel M Fernandez-Diaz Daniel D Fernandez-Marta Beatriz B Rodriguez-Vidal Cristina C Lago-Baameiro Nerea N Silva-Rodríguez Paula P Paniagua Laura L Blanco-Teijeiro María José MJ Pardo María M Piñeiro Antonio A
Cancers 20201012 10
Uveal melanoma (UM) is the most common primary intraocular tumor in adulthood. Approximately 50% of patients develop metastatic disease, which typically affects the liver and is usually fatal within one year. This type of cancer is heterogeneous in nature and is divided into two broad groups of tumors according to their susceptibility to develop metastasis. In the last decade, chromosomal abnormalities and the aberrant expression of several signaling pathways and oncogenes in uveal melanomas hav ...[more]