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ABSTRACT:
SUBMITTER: Tiwari S
PROVIDER: S-EPMC7600591 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Tiwari Sanjay S Sarolia Jayant J Kansara Vrushti V Chudasama Nishith A NA Prasad Kamalesh K Ray Debes D Aswal Vinod K VK Bahadur Pratap P
Polymers 20201001 10
This study reports targetable micelles developed after covalent functionalization of α-tocopheryl polyethylene glycol succinate (TPGS) with amino phenylboronic acid (APBA). Nuclear magnetic resonance (NMR) and infrared (IR) spectroscopic results showed successful attachment of APBA to the hydrophilic segment of TPGS. Dynamic light scattering and small-angle neutron scattering studies revealed that the conjugate self-assembled in water to produce spherical core-shell micelles (14-20 nm) which rem ...[more]