Ontology highlight
ABSTRACT:
SUBMITTER: Buchanan AH
PROVIDER: S-EPMC7605431 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Buchanan Adam H AH Lester Kirchner H H Schwartz Marci L B MLB Kelly Melissa A MA Schmidlen Tara T Jones Laney K LK Hallquist Miranda L G MLG Rocha Heather H Betts Megan M Schwiter Rachel R Butry Loren L Lazzeri Amanda L AL Frisbie Lauren R LR Rahm Alanna Kulchak AK Hao Jing J Willard Huntington F HF Martin Christa L CL Ledbetter David H DH Williams Marc S MS Sturm Amy C AC
Genetics in medicine : official journal of the American College of Medical Genetics 20200630 11
<h4>Purpose</h4>Three genetic conditions-hereditary breast and ovarian cancer syndrome, Lynch syndrome, and familial hypercholesterolemia-have tier 1 evidence for interventions that reduce morbidity and mortality, prompting proposals to screen unselected populations for these conditions. We examined the impact of genomic screening on risk management and early detection in an unselected population.<h4>Methods</h4>Observational study of electronic health records (EHR) among individuals in whom a p ...[more]