Risk of Noninfectious Uveitis with Female Hormonal Therapy in a Large Healthcare Claims Database.

ABSTRACT:

Purpose

To determine if female hormonal therapy (FHT) increases the incidence of noninfectious uveitis.

Design

Retrospective cohort study.

Participants

Women exposed to FHT and matched women unexposed to FHT enrolled in a national insurance plan.

Methods

Estimation of noninfectious uveitis incidence used multivariable Cox proportional hazards regression. To account for differences between the exposed and unexposed cohorts, a propensity score for being prescribed FHT was created using logistic regression, and inverse probability of treatment weighting was performed.

Main outcome measures

Incidence of noninfectious uveitis. For the primary outcome, incident noninfectious uveitis was defined as a new diagnosis code for noninfectious uveitis followed by a se

SUBMITTER: Sobrin L 

PROVIDER: S-EPMC7606220 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature