CLC-3 and SOX2 regulate the cell cycle in DU145 cells.
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ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC7608052 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
CLC-3 and SOX2 regulate the cell cycle in DU145 cells.
Chen Jiahong J Wang Fang F Lu Yuli Y Yang Shangqi S Chen Xueqin X Huang Youwei Y Lin Xi X
Oncology letters 20201021 6
Sex determining region Y-box 2 (SOX2) is a transcription factor that serves a role in numerous different types of malignant cancer. Altered expression of chloride channel proteins has been described in a variety of malignancies. However, the association between SOX2 and chloride channel proteins is not yet fully understood. The present study investigated the association between SOX2 and chloride voltage-gated channel 3 (CLC-3) in prostate cancer. Flow cytometry demonstrated that the inactivation ...[more]
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