Ontology highlight
ABSTRACT:
SUBMITTER: Li M
PROVIDER: S-EPMC7609060 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Li Ming M Xie Zhongyu Z Li Jinteng J Lin Jiajie J Zheng Guan G Liu Wenjie W Tang Su'an S Cen Shuizhong S Ye Guiwen G Li Zhaofeng Z Yu Wenhui W Wang Peng P Wu Yanfeng Y Shen Huiyong H
eLife 20201002
Osteoporosis is a common systemic skeletal disorder resulting in bone fragility and increased fracture risk. It is still necessary to explore its detailed mechanisms and identify novel targets for the treatment of osteoporosis. Previously, we found that a lncRNA named <i>GAS5</i> in human could negatively regulate the lipoblast/adipocyte differentiation. However, it is still unclear whether <i>GAS5</i> affects osteoblast differentiation and whether <i>GAS5</i> is associated with osteoporosis. Ou ...[more]