Dataset Information

Track Iran's national COVID-19 response committee's major concerns using two-stage unsupervised topic modeling.

ABSTRACT: Background: Since the World Health Organization (WHO) declared the COVID-19 as a Public Health Emergency of International Concern (PHEIC) on January 31, 2020, governments have been enfaced with crisis for timely responses. The efficacy of these responses directly depends on the social behaviors of the target society. People react to these actions with respect to the information they received from different channels, such as news and social networks. Thus, analyzing news demonstrates a brief view of the information users received during the outbreak.

Methods: The raw data used in this study is collected from official news channels of news wires and agencies in Telegram messenger, which exceeds 2,400,000 posts. The posts that are quoted by NCRC's members are collected, cleaned, and divided into sentences. The topic modeling and tracking are utilized in a two-stage framework, which is customized for this problem to separate miscellaneous sentences from those presenting concerns. The first stage is fed with embedding vectors of sentences where they are grouped by the Mapper algorithm. Sentences belonging to singleton nodes are labeled as miscellaneous sentences. The remained sentences are vectorized, adopting Tf-IDF weighting schema in the second stage and topically modeled by the LDA method. Finally, relevant topics are aligned to the list of policies and actions, named topic themes, that are set up by the NCRC.

Results: Our results show that major concerns presented in about half of the sentences are (1) PCR lab. test, diagnosis, and screening, (2) Closure of the education system, and (3) awareness actions about washing hands and facial mask usage. Among the eight themes, intra-provincial travel and traffic restrictions, as well as briefing the national and provincial status, are under-presented. The timeline of concerns annotated by the preventive actions illustrates the changes in concerns addressed by NCRC. This timeline shows that although the announcements and public responses are not lagged behind the events, but cannot be considered as timely. Furthermore, the fluctuating series of concerns reveal that the NCRC has not a long-time response map, and members react to the closest announced policy/act.

Conclusion: The results of our study can be used as a quantitative indicator for evaluating the availability of an on-time public response of Iran's NCRC during the first three months of the outbreak. Moreover, it can be used in comparative studies to investigate the differences between awareness acts in various countries. Results of our customized-design framework showed that about one-third of the discussions of the NCRC's members cover miscellaneous topics that must be removed from the data.

SUBMITTER: Kaveh-Yazdy F

PROVIDER: S-EPMC7609243 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Track Iran's national COVID-19 response committee's major concerns using two-stage unsupervised topic modeling.

Kaveh-Yazdy Fatemeh F Zarifzadeh Sajjad S

International journal of medical informatics 20201104

<h4>Background</h4>Since the World Health Organization (WHO) declared the COVID-19 as a Public Health Emergency of International Concern (PHEIC) on January 31, 2020, governments have been enfaced with crisis for timely responses. The efficacy of these responses directly depends on the social behaviors of the target society. People react to these actions with respect to the information they received from different channels, such as news and social networks. Thus, analyzing news demonstrates a bri ...[more]

PMID: 33181447

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Project description:BACKGROUND: The Food and Drug Administration (FDA) approved drug labels contain a broad array of information, ranging from adverse drug reactions (ADRs) to drug efficacy, risk-benefit consideration, and more. However, the labeling language used to describe these information is free text often containing ambiguous semantic descriptions, which poses a great challenge in retrieving useful information from the labeling text in a consistent and accurate fashion for comparative analysis across drugs. Consequently, this task has largely relied on the manual reading of the full text by experts, which is time consuming and labor intensive. METHOD: In this study, a novel text mining method with unsupervised learning in nature, called topic modeling, was applied to the drug labeling with a goal of discovering "topics" that group drugs with similar safety concerns and/or therapeutic uses together. A total of 794 FDA-approved drug labels were used in this study. First, the three labeling sections (i.e., Boxed Warning, Warnings and Precautions, Adverse Reactions) of each drug label were processed by the Medical Dictionary for Regulatory Activities (MedDRA) to convert the free text of each label to the standard ADR terms. Next, the topic modeling approach with latent Dirichlet allocation (LDA) was applied to generate 100 topics, each associated with a set of drugs grouped together based on the probability analysis. Lastly, the efficacy of the topic modeling was evaluated based on known information about the therapeutic uses and safety data of drugs. RESULTS: The results demonstrate that drugs grouped by topics are associated with the same safety concerns and/or therapeutic uses with statistical significance (P<0.05). The identified topics have distinct context that can be directly linked to specific adverse events (e.g., liver injury or kidney injury) or therapeutic application (e.g., antiinfectives for systemic use). We were also able to identify potential adverse events that might arise from specific medications via topics. CONCLUSIONS: The successful application of topic modeling on the FDA drug labeling demonstrates its potential utility as a hypothesis generation means to infer hidden relationships of concepts such as, in this study, drug safety and therapeutic use in the study of biomedical documents.

Project description:Disease ecology is a rapidly growing subdiscipline, and mammals and their parasites feature prominently in both historical and more recent research efforts. Nevertheless, the diversity of topics explored, and those not well explored, has not been systematically assessed. We conducted a systematic review of the published scientific literature in disease ecology of mammals and subjected the collection of original and review articles identified to a topic modeling approach, which is based on the words used in the published texts and their contexts (i.e., the frequency and strength of their semantic relationships with one another). In addition to concept maps identifying the most prominent research themes, we identified eight (not mutually exclusive) subcategories of studies, including experimental, theoretical, comparative, behavioral, immunological-microbiological, biogeographic-macroecological, vector-focused (e.g., mosquitoes), and disturbance-focused. The most prominent themes arising in review papers included the ecology of zoonotic diseases transmitted from non-human mammals, comparisons of pathogen prevalence between mammalian species, and pathogen discovery-disease surveillance studies, particularly of marine mammals and bats. For the original articles, the most prominent themes included ecology of rodent-transmitted viral and bacterial diseases and the population biology of zoonotic hosts. Most studies used comparative or descriptive approaches to investigate mammal-pathogen-disease relationships at a local scale, focusing on vector-borne diseases. Experimental, modeling, immunological, and behavioral approaches were strikingly underrepresented. Topics of strong conceptual importance, but that are underrepresented in the current literature, include: 1) the effects of the population density of mammalian hosts, and manipulations of density, on pathogen transmission; 2) macroecological studies that quantify effects of mammalian host species on parasite abundance and prevalence; and 3) effects of climate change on physiological and behavioral processes relevant to mammal-parasite interactions.

Project description:BackgroundDuring the COVID-19 pandemic, numerous countries, including China and France, have implemented lockdown measures that have been effective in controlling the epidemic. However, little is known about the impact of these measures on the population as expressed on social media from different cultural contexts.ObjectiveThis study aims to assess and compare the evolution of the topics discussed on Chinese and French social media during the COVID-19 lockdown.MethodsWe extracted posts containing COVID-19-related or lockdown-related keywords in the most commonly used microblogging social media platforms (ie, Weibo in China and Twitter in France) from 1 week before lockdown to the lifting of the lockdown. A topic model was applied independently for three periods (prelockdown, early lockdown, and mid to late lockdown) to assess the evolution of the topics discussed on Chinese and French social media.ResultsA total of 6395; 23,422; and 141,643 Chinese Weibo messages, and 34,327; 119,919; and 282,965 French tweets were extracted in the prelockdown, early lockdown, and mid to late lockdown periods, respectively, in China and France. Four categories of topics were discussed in a continuously evolving way in all three periods: epidemic news and everyday life, scientific information, public measures, and solidarity and encouragement. The most represented category over all periods in both countries was epidemic news and everyday life. Scientific information was far more discussed on Weibo than in French tweets. Misinformation circulated through social media in both countries; however, it was more concerned with the virus and epidemic in China, whereas it was more concerned with the lockdown measures in France. Regarding public measures, more criticisms were identified in French tweets than on Weibo. Advantages and data privacy concerns regarding tracing apps were also addressed in French tweets. All these differences were explained by the different uses of social media, the different timelines of the epidemic, and the different cultural contexts in these two countries.ConclusionsThis study is the first to compare the social media content in eastern and western countries during the unprecedented COVID-19 lockdown. Using general COVID-19-related social media data, our results describe common and different public reactions, behaviors, and concerns in China and France, even covering the topics identified in prior studies focusing on specific interests. We believe our study can help characterize country-specific public needs and appropriately address them during an outbreak.

Dataset Information

Track Iran's national COVID-19 response committee's major concerns using two-stage unsupervised topic modeling.

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Track Iran's national COVID-19 response committee's major concerns using two-stage unsupervised topic modeling.

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