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Concentration-driven phase transition and self-assembly in drying droplets of diluting whole blood.

ABSTRACT: Multi-colloidal systems exhibit a variety of structural and functional complexity owing to their ability to interact amongst different components into self-assembled structures. This paper presents experimental confirmations that reveal an interesting sharp phase transition during the drying state and in the dried film as a function of diluting concentrations ranging from 100% (undiluted whole blood) to 12.5% (diluted concentrations). An additional complementary contact angle measurement exhibits a monotonic decrease with a peak as a function of drying. This peak is related to a change in visco-elasticity that decreases with dilution, and disappears at the dilution concentration for the observed phase transition equivalent to 62% (v/v). This unique behavior is clearly commensurate with the optical image statistics and morphological analysis; and it is driven by the decrease in the interactions between various components within this bio-colloid. The implications of these phenomenal systems may address many open-ended questions of complex hierarchical structures.

SUBMITTER: Pal A

PROVIDER: S-EPMC7609771 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Concentration-driven phase transition and self-assembly in drying droplets of diluting whole blood.

Pal Anusuya A Gope Amalesh A Obayemi John D JD Iannacchione Germano S GS

Scientific reports 20201103 1

Multi-colloidal systems exhibit a variety of structural and functional complexity owing to their ability to interact amongst different components into self-assembled structures. This paper presents experimental confirmations that reveal an interesting sharp phase transition during the drying state and in the dried film as a function of diluting concentrations ranging from 100% (undiluted whole blood) to 12.5% (diluted concentrations). An additional complementary contact angle measurement exhibit ...[more]

PMID: 33144671

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Concentration-driven phase transition and self-assembly in drying droplets of diluting whole blood.

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Concentration-driven phase transition and self-assembly in drying droplets of diluting whole blood.

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