Ontology highlight
ABSTRACT:
SUBMITTER: Cui Y
PROVIDER: S-EPMC7609867 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Cui Yuexin Y Sun Jiejie J Hao Wenyan W Chen Mengyu M Wang Yingzi Y Xu Fenghua F Gao Chunsheng C
Frontiers in oncology 20201021
Penetration of the blood-brain barrier (BBB) and the blood-brain tumor barrier (BBTB) remains a significant challenge for the delivery of drugs in the treatment of glioma. Therefore, the development of targeted preparations with the ability to penetrate the BBB and BBTB, and target gliomas, is an important approach if we are to improve the efficacy of glioma treatment. In the current study, an active targeting preparation based on PLGA nanoparticles coated with erythrocyte membranes (RBCNPs) and ...[more]