In vitro scolicidal activity of synthesised silver nanoparticles from aqueous plant extract against Echinococcus granulosus.

ABSTRACT: At present, biosynthesis of AgNPs is a very effective method to produce less toxic nanoparticles. The vision of this research is to use three different plant extracts derived from leaves of Piper nigrum, Ziziphus Spina-Christi and Eucalyptus globulus for rapid biosynthesis of AgNPs. This is in addition to investigating the scolicidal activity against Echinococcus granulosus. The methods of UV-vis spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray analysis (EDX) were employed to characterise the nanoparticles. UV spectra disclosed a maximum absorption at 437?nm for the biosynthesised AgNPs using EUCGLO extract. The XRD patterns revealed the (fcc) structure of the AgNPs with slightly shifted characteristic peaks at 2? degree of 37.3? and 43.4?, respectively. The scolicidal activity against E. granulosus revealed that the AgNPs, which were synthesised using Eucalyptus globulus, have powered scolicidal of 47.8 % after 45?min. which is comparable to the treatment by Albendazole.

SUBMITTER: Salih TA 

PROVIDER: S-EPMC7610041 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature