Ontology highlight
ABSTRACT:
SUBMITTER: Kiesel P
PROVIDER: S-EPMC7610599 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Kiesel Petra P Alvarez Viar Gonzalo G Tsoy Nikolai N Maraspini Riccardo R Gorilak Peter P Varga Vladimir V Honigmann Alf A Pigino Gaia G
Nature structural & molecular biology 20200928 12
Primary cilia are microtubule-based organelles that are important for signaling and sensing in eukaryotic cells. Unlike the thoroughly studied motile cilia, the three-dimensional architecture and molecular composition of primary cilia are largely unexplored. Yet, studying these aspects is necessary to understand how primary cilia function in health and disease. We developed an enabling method for investigating the structure of primary cilia isolated from MDCK-II cells at molecular resolution by ...[more]