Fluorescent ROMP Monomers and Copolymers for Biomedical Applications.
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ABSTRACT: The synthesis and characterization of a series of green, blue and red-fluorescent exo-oxanorbornene acid and imide monomers carrying nitrobenzofurazan, coumarin, and Rhodamin B, respectively, as fluorophores is presented. These monomers carry oxanorbornene as polymerizable unit, and were readily copolymerized with bioactive functional oxanorbornene monomers by ring-opening metathesis polymerization (ROMP), as demonstrated by gel permeation chromatography and NMR spectroscopy. Due to the ease of synthesis of these monomers, and their cost-effectiveness compared many to other fluorescent probes, they are useful for biomaterials applications.
SUBMITTER: Riga EK
PROVIDER: S-EPMC7611511 | biostudies-literature |
REPOSITORIES: biostudies-literature
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