Improved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI.

ABSTRACT:

Purpose

Susceptibility Weighted Imaging (SWI) has become established in the clinical investigation of stroke, microbleeds, tumor vascularization, calcification and iron deposition, but suffers from a number of shortcomings and artefacts. The goal of this study was to reduce the sensitivity of SWI to strong B₁ and B₀ inhomogeneities at ultra-high field to generate homogeneous images with increased contrast and free of common artefacts. All steps in SWI processing have been addressed - coil combination, phase unwrapping, image combination over echoes, phase filtering and homogeneity correction - and applied to an efficient bipolar multi-echo acquisition to substantially improve the quality of SWI.

Principal results

Our findings regarding the optimal indiv

SUBMITTER: Eckstein K 

PROVIDER: S-EPMC7612087 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature