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Autophagy promotes programmed cell death and corpse clearance in specific cell types of the Arabidopsis root cap.


ABSTRACT: Autophagy is a conserved quality control pathway that mediates the degradation of cellular components by targeting them to the lysosomes or vacuoles.1 Autophagy has been implicated in the regulation of some regulated cell death processes in animal systems.2 However, its function in developmentally controlled programmed cell death (dPCD) in plants remains little studied and controversial.3 Some studies have reported autophagy pro-survival roles,4,5 while others have suggested pro-death functions for autophagy,6,7 calling for further detailed investigations. Here, we investigated the role of autophagy in dPCD using the Arabidopsis root cap as an accessible and genetically tractable model system

SUBMITTER: Feng Q 

PROVIDER: S-EPMC7612756 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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