Mosquito microevolution drives Plasmodium falciparum dynamics.
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ABSTRACT:
SUBMITTER: Gildenhard M
PROVIDER: S-EPMC7613322 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Mosquito microevolution drives Plasmodium falciparum dynamics.
Gildenhard Markus M Rono Evans K EK Diarra Assetou A Boissière Anne A Bascunan Priscila P Carrillo-Bustamante Paola P Camara Djeneba D Krüger Hanne H Mariko Modibo M Mariko Ramata R Mireji Paul P Nsango Sandrine E SE Pompon Julien J Reis Yara Y Rono Martin K MK Seda Pamela B PB Thailayil Janis J Traorè Alou A Yapto Cynthia V CV Awono-Ambene Parfait P Dabiré Roch K RK Diabaté Abdulaye A Masiga Daniel D Catteruccia Flaminia F Morlais Isabelle I Diallo Mouctar M Sangare Djibril D Levashina Elena A EA
Nature microbiology 20190325 6
Malaria, a major cause of child mortality in Africa, is engendered by Plasmodium parasites that are transmitted by anopheline mosquitoes. Fitness of Plasmodium parasites is closely linked to the ecology and evolution of its anopheline vector. However, whether the genetic structure of vector populations impacts malaria transmission remains unknown. Here, we describe a partitioning of the African malaria vectors into generalists and specialists that evolve along ecological boundaries. We next iden ...[more]
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