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Surgical Feasibility of a One-Stage Cell-Based Arthroscopic Procedure for Meniscus Regeneration: A Cadaveric Study.

ABSTRACT:

Impact statement

Meniscus injury remains the most common indication for orthopedic surgery, but loss of functioning meniscus tissue is strongly correlated with development of early osteoarthritis. However, current clinical options for tissue engineering of the meniscus are limited. This study demonstrates the feasibility of combining human meniscus cells with mesenchymal stromal cells to enhance a meniscus scaffold for meniscus regeneration in a one-stage solution for partial meniscal deficiency.

SUBMITTER: Hagmeijer MH

PROVIDER: S-EPMC7615694 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Surgical Feasibility of a One-Stage Cell-Based Arthroscopic Procedure for Meniscus Regeneration: A Cadaveric Study.

Hagmeijer Michella H MH Vonk Lucienne A LA Kouwenhoven Jan-Willem JW Custers Roel J H RJH Bleys Ronald L RL Krych Aaron J AJ Saris Daniel B F DBF

Tissue engineering. Part C, Methods 20181201 12

<h4>Impact statement</h4>Meniscus injury remains the most common indication for orthopedic surgery, but loss of functioning meniscus tissue is strongly correlated with development of early osteoarthritis. However, current clinical options for tissue engineering of the meniscus are limited. This study demonstrates the feasibility of combining human meniscus cells with mesenchymal stromal cells to enhance a meniscus scaffold for meniscus regeneration in a one-stage solution for partial meniscal de ...[more]

PMID: 30398399

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