Ontology highlight
ABSTRACT:
SUBMITTER: Fontanilles M
PROVIDER: S-EPMC7641818 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Acta neuropathologica communications 20201104 1
The clinical implications of plasmatic cell-free and tumor DNA (cfDNA and ctDNA) are challenging in glioblastoma. This prospective study included 52 consecutive newly diagnosed glioblastoma (n = 49) or gliosarcoma (n = 3) patients treated with concomitant temozolomide and radiotherapy (RT-TMZ), followed by a TMZ maintenance phase. Plasma samples were collected at baseline, before RT-TMZ (pre-RT-TMZ) and at the end of adjuvant TMZ, or at the time of progression in cases of progressive disease (PD ...[more]