Non-linear association between diabetes mellitus and pulmonary function: a population-based study.

ABSTRACT:

Background

There is increasing evidence that the lung is a target organ of diabetes. This study aimed to examine in detail the association between diabetes mellitus and pulmonary function using a national cohort. We also aimed to explore the non-linear association between pulmonary function and blood glucose, insulin resistance, and C-reactive protein (CRP).

Methods

A total of 30,442 participants from the National Health and Nutrition Examination Survey from the period between 2007 and 2012 were included. The cross-sectional association between diabetes mellitus and pulmonary function was assessed using multiple linear regression. Where there was evidence of non-linearity, we applied a restricted cubic spline with three knots to explore the non-linear association. Partial me

SUBMITTER: Zhang RH 

PROVIDER: S-EPMC7641838 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature