Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis.
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ABSTRACT:
SUBMITTER: Smelror RE
PROVIDER: S-EPMC7641937 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
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Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis.
Smelror Runar Elle RE Rund Bjørn Rishovd BR Lonning Vera V Jørgensen Kjetil Nordbø KN Wedervang-Resell Kirsten K Andreassen Ole A OA Ueland Torill T Myhre Anne M AM Agartz Ingrid I
European child & adolescent psychiatry 20200208 12
Neurocognitive deficits are associated with impaired global functioning and psychotic symptoms. However, whether symptoms can mediate the relationship between neurocognition and global functioning in adolescent psychosis is unclear. Here, we investigated if symptoms assessed with the Positive And Negative Syndrome Scale (PANSS), mediated the relationship between neurocognitive performance and global functioning in adolescents with non-affective early-onset psychotic disorders (EOP). Sixty-one ad ...[more]
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