Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC7641969 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wang Hao H Xie Xin X He Wei W Wang Yuxu Y Ren Tongwei T Ouyang Kang K Chen Ying Y Huang Weijian W Wei Zuzhang Z
Frontiers in veterinary science 20201022
Porcine reproductive and respiratory syndrome virus (PRRSV) has been used as a gene expression vector in the development of vaccines. Most of these recombinant PRRSV vectors express only a single foreign gene through either an internal insertion in the hypervariable region of nsp2 or expression cassette and some of these recombinant vectors are genetically unstable. Here, we combined internal insertion in nsp2 and expression cassette methods to generate a novel recombinant PRRSV stably expressin ...[more]