Ontology highlight
ABSTRACT:
SUBMITTER: Custodio TF
PROVIDER: S-EPMC7642358 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Nature communications 20201104 1
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Therapeutic neutralizing antibodies constitute a key short-to-medium term approach to tackle COVID-19. However, traditional antibody production is hampered by long development times and costly production. Here, we report the rapid isolation and characterization of nanobodies from a synthetic library, known as sybodies (Sb), that target the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. Several binders with ...[more]