Ontology highlight
ABSTRACT:
SUBMITTER: Tlemsani C
PROVIDER: S-EPMC7643325 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Tlemsani Camille C Pongor Lorinc L Elloumi Fathi F Girard Luc L Huffman Kenneth E KE Roper Nitin N Varma Sudhir S Luna Augustin A Rajapakse Vinodh N VN Sebastian Robin R Kohn Kurt W KW Krushkal Julia J Aladjem Mirit I MI Teicher Beverly A BA Meltzer Paul S PS Reinhold William C WC Minna John D JD Thomas Anish A Pommier Yves Y
Cell reports 20201001 3
CellMiner-SCLC (https://discover.nci.nih.gov/SclcCellMinerCDB/) integrates drug sensitivity and genomic data, including high-resolution methylome and transcriptome from 118 patient-derived small cell lung cancer (SCLC) cell lines, providing a resource for research into this "recalcitrant cancer." We demonstrate the reproducibility and stability of data from multiple sources and validate the SCLC consensus nomenclature on the basis of expression of master transcription factors NEUROD1, ASCL1, POU ...[more]