Ontology highlight
ABSTRACT:
SUBMITTER: Ahmed MS
PROVIDER: S-EPMC7643350 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Neuron 20200508 2
Episodic memory requires linking events in time, a function dependent on the hippocampus. In "trace" fear conditioning, animals learn to associate a neutral cue with an aversive stimulus despite their separation in time by a delay period on the order of tens of seconds. But how this temporal association forms remains unclear. Here we use two-photon calcium imaging of neural population dynamics throughout the course of learning and show that, in contrast to previous theories, hippocampal CA1 does ...[more]