Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC7644538 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Li Jinguang J Ren Honghong H He Ying Y Li ZongChang Z Ma Xiaoqian X Yuan Liu L Ouyang Lijun L Zhou Jun J Wang Dong D Li Chunwang C Chen Xiaogang X Han Hongying H Tang Jinsong J
Frontiers in psychiatry 20201023
The glutamatergic system has previously been shown to be involved in the pathophysiology of schizophrenia and the mechanisms of action of antipsychotic treatment. The present study aimed to investigate the relationship between the levels of glutamate (Glu) or Glu/total creatine (Glu/Cr+PCr) in the anterior cingulate cortex (ACC) and psychiatric symptoms as well as the response to antipsychotic treatment. We performed proton magnetic resonance spectroscopy (<sup>1</sup>H-MRS) to measure Glu and G ...[more]