Elfin UI: A Graphical Interface for Protein Design With Modular Building Blocks.

ABSTRACT: Molecular models have enabled understanding of biological structures and functions and allowed design of novel macro-molecules. Graphical user interfaces (GUIs) in molecular modeling are generally focused on atomic representations, but, especially for proteins, do not usually address designs of complex and large architectures, from nanometers to microns. Therefore, we have developed Elfin UI as a Blender add-on for the interactive design of large protein architectures with custom shapes. Elfin UI relies on compatible building blocks to design single- and multiple-chain protein structures. The software can be used: (1) as an interactive environment to explore building blocks combinations; and (2) as a computer aided design (CAD) tool to define target shapes that guide automated design. Elfi

SUBMITTER: Yeh CT 

PROVIDER: S-EPMC7644802 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature