Ontology highlight
ABSTRACT:
SUBMITTER: Ning W
PROVIDER: S-EPMC7647696 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Ning Wanshan W Xu Haodong H Jiang Peiran P Cheng Han H Deng Wankun W Guo Yaping Y Xue Yu Y
Genomics, proteomics & bioinformatics 20200401 2
As an important protein acylation modification, lysine succinylation (Ksucc) is involved in diverse biological processes, and participates in human tumorigenesis. Here, we collected 26,243 non-redundant known Ksucc sites from 13 species as the benchmark data set, combined 10 types of informative features, and implemented a hybrid-learning architecture by integrating deep-learning and conventional machine-learning algorithms into a single framework. We constructed a new tool named HybridSucc, whi ...[more]