Unknown

Dataset Information

0

Liquid Biopsy in Breast Cancer.


ABSTRACT: In recent years, the blood-based analysis of circulating tumour cells (CTCs) and nucleic acids (DNA/RNA), otherwise known as liquid biopsy, has become increasingly important in breast cancer. Numerous trials have already underscored the high prognostic significance of CTC detection in both early and metastatic stages. Moreover, the changes in CTC levels and circulating tumour DNA (ctDNA) during the course of the disease correlate with the response to treatment. Research currently focuses on liquid-biopsy based therapeutic interventions in metastatic breast cancer. In this context, alpelisib, a PI3K inhibitor, was the first agent to be approved by FDA and EMA.

SUBMITTER: Banys-Paluchowski M 

PROVIDER: S-EPMC7647718 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

altmetric image

Publications

Liquid Biopsy in Breast Cancer.

Banys-Paluchowski Maggie M   Krawczyk Natalia N   Fehm Tanja T  

Geburtshilfe und Frauenheilkunde 20201106 11


In recent years, the blood-based analysis of circulating tumour cells (CTCs) and nucleic acids (DNA/RNA), otherwise known as liquid biopsy, has become increasingly important in breast cancer. Numerous trials have already underscored the high prognostic significance of CTC detection in both early and metastatic stages. Moreover, the changes in CTC levels and circulating tumour DNA (ctDNA) during the course of the disease correlate with the response to treatment. Research currently focuses on liqu  ...[more]

Similar Datasets

| S-EPMC9105073 | biostudies-literature
| S-EPMC5797586 | biostudies-literature
| S-EPMC8209161 | biostudies-literature
| S-EPMC8964955 | biostudies-literature
| S-EPMC5528975 | biostudies-literature
| S-EPMC8130163 | biostudies-literature
| S-EPMC5130002 | biostudies-literature
| S-EPMC6507432 | biostudies-literature
| S-EPMC7460238 | biostudies-literature
| S-EPMC11218356 | biostudies-literature