Variation in the stearoyl-CoA desaturase gene (SCD) and its influence on milk fatty acid composition in late-lactation dairy cattle grazed on pasture.

ABSTRACT: Gene markers have become useful tools for improving animal genetics and breeding since they improve the accuracy of selection for superior breeding stock. In this study, the stearoyl-CoA desaturase ( Δ -9-desaturase) gene (SCD) was investigated in New Zealand pasture-grazed Holstein-Friesian  ×  Jersey cows. Three nucleotide substitutions were identified in exon 5 of the gene (c.702A/G, c.762T/C and c.878C/T), and a single nucleotide substitution was identified in intron 5 (c.880 + 105A/G). The c.878C/T substitution would, if expressed, result in the amino acid substitution p.A293V. Four nucleotide substitutions (c.*1783A/G, c.*1883C/T, c.*1984G/A and c.*2066T/C/G) were identified in the 3 ' -untranslated region (3 ' -UTR), and these resulted in three nucleotide sequence variant

SUBMITTER: Li Y 

PROVIDER: S-EPMC7648274 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature