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Skin Recovery After Discontinuation of Long-Term Moisturizer Application: A Split-Face Comparison Pilot Study.

ABSTRACT: INTRODUCTION:Facial moisturizers are commonly used by healthy women and increasingly men of all age groups. This study aimed to investigate the effects of moisturizer discontinuation and the subsequent evolution of symptoms. METHODS:Two prospective observational split-face comparison pilot studies were performed in Switzerland and enrolled (I) 20 healthy women aged 17-25 years in winter and (II) 36 female subjects 15-20 and 40-55 years of age in summer. Moisturizers were stopped on the investigational half of the face. On the control side, the usual skin care regimen was continued. Daily subjective (I/II) and objective (I) skin assessments for the occurrence of typical symptoms of dry skin (dryness, itching, scales, redness, wrinkles) were collected. RESULTS:In the winter study (cohort I) in both the subjective and objective assessment, all skin changes increased significantly within 1 day after discontinuation. On day 7, dryness (p?

SUBMITTER: Maul JT 

PROVIDER: S-EPMC7649173 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Skin Recovery After Discontinuation of Long-Term Moisturizer Application: A Split-Face Comparison Pilot Study.

Maul Julia-Tatjana JT   Maul Lara Valeska LV   Kägi Marc M   Cheng Phil P   Anzengruber Florian F   von Laue Mathilde M   Chen Yuki Y   Kägi Martin M   Navarini Alexander A  

Dermatology and therapy 20201007 6

<h4>Introduction</h4>Facial moisturizers are commonly used by healthy women and increasingly men of all age groups. This study aimed to investigate the effects of moisturizer discontinuation and the subsequent evolution of symptoms.<h4>Methods</h4>Two prospective observational split-face comparison pilot studies were performed in Switzerland and enrolled (I) 20 healthy women aged 17-25 years in winter and (II) 36 female subjects 15-20 and 40-55 years of age in summer. Moisturizers were stopped o  ...[more]

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