Ontology highlight
ABSTRACT:
SUBMITTER: Milone G
PROVIDER: S-EPMC7649636 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Milone Giuseppe G Conticello Concetta C Leotta Salvatore S Michieli Maria Grazia MG Martino Massimo M Marco Anna Lia Di ALD Spadaro Andrea A Cupri Alessandra A Condorelli Annalisa A Milone Giulio Antonio GA Markovic Uros U Sciortino Roberta R Schininà Giovanni G Moschetti Gaetano G Villari Loredana L Saccardi Riccardo R
Leukemia research reports 20201030
In CD34+ cells mobilization of patients with multiple myeloma (MM), the use of Cyclophosphamide (CTX) at a dose of 2 g/m<sup>2</sup> has low efficacy although also lower toxicity. The suboptimal mobilizing effect of low-dose CTX, however, may be overcome by plerixafor (PLX) on demand. We conducted a prospective multicenter study in 138 patients with MM to evaluate CTX 2 g/m<sup>2</sup> in association with granulocyte-colony stimulating factor (G-CSF) and on-demand PLX. We compared results with a ...[more]