Ontology highlight
ABSTRACT:
SUBMITTER: Klose AM
PROVIDER: S-EPMC7650819 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Klose Alanna M AM Miller Benjamin L BL
Sensors (Basel, Switzerland) 20201010 20
While label-free multiplex sensor technology enables "mixing and matching" of different capture molecules in principle, in practice this has been rarely (if ever) demonstrated. To fill this gap, we developed protocols for the preparation of mixed aptamer-protein arrays on the arrayed imaging reflectometry (AIR) sensing platform using streptavidin as a common attachment point for both biotinylated proteins and aptamers. Doing so required overcoming the noted instability of dried streptavidin mono ...[more]