Ontology highlight
ABSTRACT:
SUBMITTER: Kagaya K
PROVIDER: S-EPMC7652394 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Kagaya Katsushi K Noma-Takayasu Naoto N Yamamoto Io I Tashiro Sanki S Ishikawa Fuyuki F Hayashi Makoto T MT
Life science alliance 20201026 12
Chromosome fusion is a frequent intermediate in oncogenic chromosome rearrangements and has been proposed to cause multiple tumor-driving abnormalities. In conventional experimental systems, however, these abnormalities were often induced by randomly induced chromosome fusions involving multiple different chromosomes. It was therefore not well understood whether a single defined type of chromosome fusion, which is reminiscent of a sporadic fusion in tumor cells, has the potential to cause chromo ...[more]