Ontology highlight
ABSTRACT:
SUBMITTER: Grist JT
PROVIDER: S-EPMC7652549 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Kidney international 20200622 5
Sodium magnetic resonance imaging (MRI) is a powerful, non-invasive technique to assess sodium distribution within the kidney. Here we undertook pre-clinical and clinical studies to quantify the corticomedullary sodium gradient in healthy individuals and in a porcine model of diuresis. The results demonstrated that sodium MRI could detect spatial differences in sodium biodistribution across the kidney. The sodium gradient of the kidney changed significantly after diuresis in the pig model and wa ...[more]