Paired rRNA-depleted and polyA-selected RNA sequencing data and supporting multi-omics data from human T cells.
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ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC7652884 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Paired rRNA-depleted and polyA-selected RNA sequencing data and supporting multi-omics data from human T cells.
Chen Li L Yang Ruirui R Kwan Tony T Tang Chao C Watt Stephen S Zhang Yiming Y Bourque Guillaume G Ge Bing B Downes Kate K Frontini Mattia M Ouwehand Willem H WH Lin Jing-Wen JW Soranzo Nicole N Pastinen Tomi T Chen Lu L
Scientific data 20201109 1
Both poly(A) enrichment and ribosomal RNA depletion are commonly used for RNA sequencing. Either has its advantages and disadvantages that may lead to biases in the downstream analyses. To better access these effects, we carried out both ribosomal RNA-depleted and poly(A)-selected RNA-seq for CD4<sup>+</sup> T naive cells isolated from 40 healthy individuals from the Blueprint Project. For these 40 individuals, the genomic and epigenetic data were also available. This dataset offers a unique opp ...[more]
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