Ontology highlight
ABSTRACT:
SUBMITTER: Shen X
PROVIDER: S-EPMC7653602 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Shen Xuanlin X Ding Yuting Y Lu Feng F Yuan Haitao H Luan Wenkang W
American journal of translational research 20201015 10
Long noncoding RNAs (lncRNAs) play the critical biological role in many malignant tumours. MIR4435-2HG has been proven to be a novel oncogenic lncRNA. However, the exact role and mechanism of MIR4435-2HG in hepatocellular carcinoma (HCC) remain unclear. Here, we found that MIR4435-2HG is overexpressed in HCC tissue compared to normal controls and that high level of MIR4435-2HG indicates a poorer prognosis in HCC patients. MIR4435-2HG enhances the growth and metastasis ability of HCC cells. MIR44 ...[more]