Differential Expression of PEG10 Contributes to Aggressive Disease in Early Versus Late-Onset Colorectal Cancer.
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ABSTRACT:
SUBMITTER: Watson KM
PROVIDER: S-EPMC7653836 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Differential Expression of PEG10 Contributes to Aggressive Disease in Early Versus Late-Onset Colorectal Cancer.
Watson Katherine M KM Gardner Ivy H IH Byrne Raphael M RM Ruhl Rebecca R RR Lanciault Christian P CP Dewey Elizabeth N EN Anand Sudarshan S Tsikitis Vassiliki Liana VL
Diseases of the colon and rectum 20201201 12
<h4>Background</h4>Colorectal cancer is a leading cause of cancer-related death. Early onset colorectal cancer (age ≤45 y) is increasing and associated with advanced disease. Although distinct molecular subtypes of colorectal cancer have been characterized, it is unclear whether age-related molecular differences exist.<h4>Objective</h4>We sought to identify differences in gene expression between early and late-onset (age ≥65 y) colorectal cancer.<h4>Design</h4>We performed a review of our instit ...[more]
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