Ontology highlight
ABSTRACT:
SUBMITTER: Borodina I
PROVIDER: S-EPMC7653990 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Borodina Irina I Kenny Louise C LC McCarthy Cathal M CM Paramasivan Kalaivani K Pretorius Etheresia E Roberts Timothy J TJ van der Hoek Steven A SA Kell Douglas B DB
Nutrition research reviews 20200213 2
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in mushroom fruiting bodies) and actinobacteria, but is not synthesised by plants and animals who acquire it via the soil and their diet, respectively. Animals have evolved a highly selective transporter for it, known as solute carrier family 22, member 4 (SLC22A4) in humans, signifying its importance, and ERG may even ...[more]