Emerging agents and regimens for multiple myeloma.
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ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC7654052 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Emerging agents and regimens for multiple myeloma.
Yang Yang Y Li Yi Y Gu Huiyao H Dong Mengmeng M Cai Zhen Z
Journal of hematology & oncology 20201109 1
The outcomes of multiple myeloma (MM) have been improved significantly with the therapies incorporating proteasome inhibitors (PI), immunomodulatory drugs, monoclonal antibodies (MoAb) and stem cell transplantation. However, relapsed and refractory MM (RRMM) remains a major challenge. Novel agents and regimens are under active clinical development. These include new PIs such as ixazomib, marizomib, and oprozomib; new MoAbs such as isatuximab and MOR202; novel epigenetic agent ricolinostat and no ...[more]
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