Cytoplasmic sharing through apical membrane remodeling.
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ABSTRACT:
SUBMITTER: Peterson NG
PROVIDER: S-EPMC7655102 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Cytoplasmic sharing through apical membrane remodeling.
Peterson Nora G NG Stormo Benjamin M BM Schoenfelder Kevin P KP King Juliet S JS Lee Rayson Rs RR Fox Donald T DT
eLife 20201014
Multiple nuclei sharing a common cytoplasm are found in diverse tissues, organisms, and diseases. Yet, multinucleation remains a poorly understood biological property. Cytoplasm sharing invariably involves plasma membrane breaches. In contrast, we discovered cytoplasm sharing without membrane breaching in highly resorptive <i>Drosophila</i> rectal papillae. During a six-hour developmental window, 100 individual papillar cells assemble a multinucleate cytoplasm, allowing passage of proteins of at ...[more]
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