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Blocking mu-opioid receptors inhibits social bonding in rituals.


ABSTRACT: Religious rituals are universal human practices that play a seminal role in community bonding. In two experiments, we tested the role of mu-opioids as the active factor fostering social bonding. We used a mu-opioid blocker (naltrexone) in two double-blind studies of rituals from different religious traditions. We found the same effect across both studies, with naltrexone leading to significantly lower social bonding compared with placebo. These studies suggest that mu-opioids play a significant role in experiences of social bonding within ritual contexts.

SUBMITTER: Charles SJ 

PROVIDER: S-EPMC7655482 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Blocking mu-opioid receptors inhibits social bonding in rituals.

Charles S J SJ   Farias M M   van Mulukom V V   Saraswati A A   Dein S S   Watts F F   Dunbar R I M RIM  

Biology letters 20201014 10


Religious rituals are universal human practices that play a seminal role in community bonding. In two experiments, we tested the role of mu-opioids as the active factor fostering social bonding. We used a mu-opioid blocker (naltrexone) in two double-blind studies of rituals from different religious traditions. We found the same effect across both studies, with naltrexone leading to significantly lower social bonding compared with placebo. These studies suggest that mu-opioids play a significant  ...[more]

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