Numerical study of the effect of channel aspect ratio on particle focusing in acoustophoretic devices.

ABSTRACT: Acoustophoretic microfluidic devices are promising non-contact and high-throughput tools for particle manipulation. Although the effectiveness of this technique has been widely demonstrated for applications based on micrometer-sized particles, the manipulation and focusing of sub-micrometer ones is challenging due to the presence of acoustic streaming. In this article, our study has the aim to investigate and understand which geometrical parameters could be changed to limit the acoustic streaming effect. We numerically study the well-known rectangular cross section of a microfluidic channel and perform a parametric study of the aspect ratio for several particle sizes. The efficiency of the focusing, is explored for different sized particles in order to identify a trend for which the acoust

SUBMITTER: Spigarelli L 

PROVIDER: S-EPMC7655847 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature