Nicotinamide N-Methyltransferase Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer.
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ABSTRACT:
SUBMITTER: Wu M
PROVIDER: S-EPMC7655872 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Nicotinamide N-Methyltransferase Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer.
Wu Miaowei M Hu Weilei W Wang Guosheng G Yao Yihan Y Yu Xiao-Fang XF
Frontiers in genetics 20201028
Gastric cancer (GC) is the third most common cause of cancer-related death in the word. Immunotherapy is a promising treatment of cancer. However, it is unclear which GC subpopulation would benefit most from immunotherapy and it is necessary to develop effective biomarkers for predicting immunotherapy response. Nicotinamide N-methyltransferase (NNMT) is a metabolic regulator of cancer-associated fibroblast (CAF) differentiation and cancer progression. In this study, we explored the correlations ...[more]
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