Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Benavides G
PROVIDER: S-EPMC7656171 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Sánchez-Benavides Gonzalo G Salvadó Gemma G Arenaza-Urquijo Eider M EM Grau-Rivera Oriol O Suárez-Calvet Marc M Milà-Alomà Marta M González-de-Echávarri José María JM Minguillon Carolina C Crous-Bou Marta M Niñerola-Baizán Aida A Perissinotti Andrés A Gispert Juan Domingo JD Molinuevo José Luis JL
Alzheimer's & dementia (Amsterdam, Netherlands) 20201111 1
<h4>Introduction</h4>Amyloid beta (Aβ) pathology is an Alzheimer's disease early hallmark. Here we assess the value of longitudinal self- and informant reports of cognitive decline to predict Aβ positron emission tomography (PET) outcome in cognitively unimpaired middle-aged individuals.<h4>Methods</h4>A total of 261 participants from the ALFA+ study underwent [<sup>18</sup>F]flutemetamol PET and Subjective Cognitive Decline Questionnaire (SCD-Q) concurrently, and 3 years before scan. We used lo ...[more]