Ontology highlight
ABSTRACT:
SUBMITTER: Joslin SEK
PROVIDER: S-EPMC7658388 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Joslin Shannon E K SEK Durbin-Johnson Blythe P BP Britton Monica M Settles Matthew L ML Korf Ian I Lemay Danielle G DG
Frontiers in genetics 20201029
Among people of European descent, the ability to digest lactose into adulthood arose via strong positive selection of a highly advantageous allele encompassing the lactase gene. Lactose-tolerant and intolerant individuals may have different disease risks due to the shared genetics of their haplotype block. Therefore, the overall objective of the study was to assess the genetic association of the lactase persistence haplotype to disease risk. Using data from the 1000Genomes project, we estimated ...[more]