Ontology highlight
ABSTRACT:
SUBMITTER: Corominas H
PROVIDER: S-EPMC7658611 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Corominas Hèctor H Castellví Ivan I Pomar Virginia V Antonijoan Rosa R Mur Isabel I Matas Laia L Gich Ignasi I de Benito Natividad N Laiz Ana A Castillo Diego D Villamarin Laura L Filella David D Millán Ana Milena AM Quijada María Ángeles MÁ Puig Mireia M Casademont Jordi J Domingo Pere P
Clinical immunology (Orlando, Fla.) 20201112
Although the starting event in COVID-19 is a viral infection some patients present with an over-exuberant inflammatory response, leading to acute lung injury (ALI) and adult respiratory distress syndrome (ARDS). Since IL-6 plays a critical role in the inflammatory response, we assessed the efficacy and safety of tocilizumab (TCZ) in this single-centre, observational study in all Covid-19 in-patient with a proven SARS-CoV-2 rapidly progressing infection to prevent ALI and ARDS. 104 patients with ...[more]