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Differential response to intravitreal dexamethasone implant in naive and previously treated diabetic macular edema eyes.

ABSTRACT: BACKGROUND:To identify different response patterns to intravitreal dexamethasone implants (IDI) in naïve and previously treated (PT) diabetic macular edema (DME) eyes in a real-life setting. METHODS:342 IDI injections (203 DME eyes) were included. Number of IDI injections, percentage (%) of eyes with 1, 2, 3 and???4 injections, time to reinjections, visual acuity (VA), intraocular pressure (IOP) and central retinal thickness (CRT) were evaluated for naïve and PT DME eyes over 24?months. RESULTS:Mean number of injections was significantly lower in naïve vs PT DME eyes (1.40?±?0.9 vs 1.82?±?0.9, p 

SUBMITTER: Zarranz-Ventura J 

PROVIDER: S-EPMC7659223 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Differential response to intravitreal dexamethasone implant in naïve and previously treated diabetic macular edema eyes.

Zarranz-Ventura Javier J   Romero-Núñez Barbara B   Bernal-Morales Carolina C   Velazquez-Villoria Daniel D   Sala-Puigdollers Anna A   Figueras-Roca Marc M   Copete Sergio S   Distefano Laura L   Boixadera Anna A   García-Arumi Jose J   Adan Alfredo A  

BMC ophthalmology 20201111 1

<h4>Background</h4>To identify different response patterns to intravitreal dexamethasone implants (IDI) in naïve and previously treated (PT) diabetic macular edema (DME) eyes in a real-life setting.<h4>Methods</h4>342 IDI injections (203 DME eyes) were included. Number of IDI injections, percentage (%) of eyes with 1, 2, 3 and ≥ 4 injections, time to reinjections, visual acuity (VA), intraocular pressure (IOP) and central retinal thickness (CRT) were evaluated for naïve and PT DME eyes over 24 m  ...[more]

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