Ontology highlight
ABSTRACT:
SUBMITTER: Kesarwani S
PROVIDER: S-EPMC7659708 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Kesarwani Shubham S Lama Prakash P Chandra Anchal A Reddy P Purushotam PP Jijumon A S AS Bodakuntla Satish S Rao Balaji M BM Janke Carsten C Das Ranabir R Sirajuddin Minhajuddin M
The Journal of cell biology 20201001 10
Microtubule cytoskeleton exists in various biochemical forms in different cells due to tubulin posttranslational modifications (PTMs). Tubulin PTMs are known to affect microtubule stability, dynamics, and interaction with MAPs and motors in a specific manner, widely known as tubulin code hypothesis. At present, there exists no tool that can specifically mark tubulin PTMs in living cells, thus severely limiting our understanding of their dynamics and cellular functions. Using a yeast display libr ...[more]