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Exome Sequencing of Native Populations From the Amazon Reveals Patterns on the Peopling of South America.

ABSTRACT: Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon region and draw insights into the peopling of South America. By using the sequence data generated here together with data from the public domain, we confirmed a strong genetic distinction between Andean and Amazonian populations. By testing distinct demographic models, our analysis supports a scenario of South America occupation that involves migrations along the Pacific and Atlantic coasts. Occupation of the southeast part of South America would involve migrations from the north, rather than from the west of the continent.

SUBMITTER: Ribeiro-Dos-Santos AM

PROVIDER: S-EPMC7660019 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Exome Sequencing of Native Populations From the Amazon Reveals Patterns on the Peopling of South America.

Ribeiro-Dos-Santos André M AM Vidal Amanda Ferreira AF Vinasco-Sandoval Tatiana T Guerreiro João J Santos Sidney S Ribeiro-Dos-Santos Ândrea Â de Souza Sandro J SJ

Frontiers in genetics 20201029

Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon region and draw insights into the peopling of South America. By using the sequence data generated here together with data from the public domain, we confirmed a strong genetic distinction between Andean an ...[more]

PMID: 33193622

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Exome sequencing for Amazon native populations

Project description:Exome sequencing for Amazon native populations

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