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A cross-sectional study of gastrointestinal symptoms, depressive symptoms and trait anxiety in young adults.


ABSTRACT: BACKGROUND:>Patients with functional gastrointestinal disorders have a high psychiatric co-morbidity. This study aimed to investigate and characterise gastrointestinal symptoms in relation to depressive symptoms and trait anxiety in a well-defined population of young adult psychiatric outpatients and healthy controls. METHODS:Gastrointestinal symptoms were assessed with the Gastrointestinal Symptom Rating Scale for Irritable Bowel Syndrome (GSRS-IBS). Depressive symptoms were assessed with the Montgomery-Åsberg Depression Rating Scale- Self assessment (MADRS-S). Trait anxiety was estimated with three of the Swedish universities of Personality (SSP) scales: Somatic trait anxiety, Psychic trait anxiety and Stress susceptibility. Self-ratings were collected from 491 young adult psychiatric outpatients and 85 healthy controls. Gastrointestinal symptom severity was compared between patients with and without current psychotropic medication and controls. Associations between gastrointestinal symptoms, depressive symptoms and trait anxiety were assessed using Spearman's coefficients and generalized linear models adjusting for possible confounders (sex, body mass index, bulimia nervosa). RESULTS:Patients, with and without current psychotropic medication, reported significantly more gastrointestinal symptoms than controls. In the generalized linear models, total MADRS-S score (p?

SUBMITTER: Soderquist F 

PROVIDER: S-EPMC7661167 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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A cross-sectional study of gastrointestinal symptoms, depressive symptoms and trait anxiety in young adults.

Söderquist Fanny F   Syk Mikaela M   Just David D   Kurbalija Novicic Zorana Z   Rasmusson Annica J AJ   Hellström Per M PM   Ramklint Mia M   Cunningham Janet L JL  

BMC psychiatry 20201111 1


<h4>Background</h4>>Patients with functional gastrointestinal disorders have a high psychiatric co-morbidity. This study aimed to investigate and characterise gastrointestinal symptoms in relation to depressive symptoms and trait anxiety in a well-defined population of young adult psychiatric outpatients and healthy controls.<h4>Methods</h4>Gastrointestinal symptoms were assessed with the Gastrointestinal Symptom Rating Scale for Irritable Bowel Syndrome (GSRS-IBS). Depressive symptoms were asse  ...[more]

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